Global nucleic acid isolation and purification market is projected to witness a CAGR of 8.06% during the forecast period 2024-2031F, growing from USD 4.89 billion in 2023 to USD 9.1 billion in 2031F. The growth of the market is supported by the expansion of healthcare sector, increasing burden of genetic diseases, technological advancements in nucleic acid isolation and purification, and rising requirement from molecular diagnostics.
The increasing burden of various genetic diseases, including cancer, in various regions across the globe is one of the major global nucleic acid isolation and purification market trends. According to the estimates of the National Cancer Institute, in 2022, approximately 20 million new cases of cancer were reported across the globe. By 2040, the number is expected to increase to 29.9 million. The rise is propelling the requirement for nucleic acid isolation and purification instruments and kits from research institutes as studying nucleic acids helps researchers gain insights into such diseases. The research aids in improving the understanding of genetic mechanisms behind such conditions, enabling the development of novel interventions, early diagnostic tests, and new treatments.
Advancements in technology, including the development of automated nucleic acid isolation and purification systems, are bolstering the global nucleic acid isolation and purification market size. Rising efforts to develop such devices can be attributed to the growing requirement for increased throughput, accuracy, and reproducibility while processing samples with a high degree of purity.
Various companies are investing towards the development of modular instruments that are capable of working together with the help of connected software for addressing complete workflows including, extraction, sample preparation, and downstream preparation of nucleic acids that have been purified for several applications. The isolation of high-quality nucleic acids is essential for various downstream applications including genetic engineering, life sciences, forensics, diagnostics, and sequencing.
Expansion of Molecular Diagnostics Sector Boosts Market Demand
The rising requirement for molecular diagnostics is boosting the global demand for nucleic acid isolation and purification. The growing requirement of molecular diagnostics can be attributed to their increasing utilization in guiding patient management, treatment, and diagnosis, particularly in the arena of congenital abnormalities, cancer, and infectious diseases. The rising requirement for molecular diagnostics is supported by the increasing awareness about the benefits offered by personalized medicines and growing prevalence of chronic diseases.
According to the estimates of the National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), six out of ten Americans live with at least one chronic health condition. Molecular diagnostics is essential for improving the treatment and diagnosis of a broad range of diseases, resulting in better patient outcomes. Thus, the growing requirement for molecular diagnostics will propel the demand for nucleic acid isolation and purification kits and instruments.
Increasing Emphasis on Research and Development Activities
The rising investments by various organizations towards research and development activities are providing lucrative growth opportunities to the market. Such activities allow the development of novel technologies that support the expansion of the market. For instance, in February 2023, BioEcho Life Sciences announced they had received two new patents from the Japan Patent Office and the United States Patent and Trademark Office. The patent called “Rapid purification of high-quality nucleic acids from biological samples" will aid the company in strengthening its intellectual property portfolio. The EchoLUTION technology developed by the company supports DNA and RNA extraction in a single centrifugation step. The patent strengthens the company’s position as a transformation driver for various processes in biopharmaceutical research, academics, and molecular diagnostics. Such developments are expected to support the expansion of the market in the coming years.
North America Accounts for a Significant Market Share
The expansion of the market in North America is supported by the increasing investments by the government and research institutes towards molecular biology and genomics, rapid growth of the pharmaceutical and biotechnology sectors in the region, and strong presence of various market players. The consistent research and development efforts coupled with the presence of a favorable regulatory framework is boosting the growth of North America nucleic acid isolation and purification market. The increasing investments in biotechnology sector is expected to boost the requirement for nucleic acid isolation and purification kits and instruments in the coming years. In 2023, the biotech firms in the United States attracted a total funding of USD 56.79 billion. The rising requirement for personalized medicines due to the rapid expansion of the healthcare sector is another major factor augmenting the growth of the market in the region.
DNA Isolation and Purification Expected to Witness Significant Growth
The expansion of the segment can be attributed to the importance of DNA extraction in studying the different genetic causes associated with a disease. It is important for developing diagnostics and drugs, carrying out sequencing genomes, and detecting viruses and bacteria, among others. The introduction of novel products by various leading market players is another major factor supporting the expansion of the segment. In May 2024, One BioMed launched X8 HMW DNA Cartridge Kits. The kits are capable of extracting high molecular weight (HMW) DNA in an automated manner, for usage in genome assembly and long-read sequencing. The kit is the world’s first automated platform to extract high molecular weight DNA from various sample types such as cell culture, peripheral blood mononuclear cells, bacteria, etc. The company’s patented Xceler8 technology is expected to redefine nucleic acid extraction by utilizing a rapid and gentle chemistry-based approach for selectively binding, clustering, and purifying intact DNA with the help of controlled fluidics.
Hospitals and Diagnostic Centers Hold Significant Market Share
The rising requirement for nucleic acid isolation and purification instruments and kits from the hospitals and diagnostic centers can be attributed to the growing prevalence of various genetic diseases and disorders across the globe. According to the estimates of the National Health, Lung, and Blood Institute, in a year, sickle cell amenia affects approximately 20 million individuals across the globe. Hospitals and diagnostic centers are heavily investing in advanced and innovative diagnostic equipment to enhance the care and services provided to the patients. RNA and DNA purification and isolation techniques are some of the efficient techniques that are deployed for diagnosing various genetic diseases inducing cystic fibrosis, sickle cell anemia, down’s syndrome, and others. Furthermore, the growing emergence of new diagnostic assays and rising requirement for point-of-care testing is augmenting the demand for nucleic acid isolation and purification processes that can be easily incorporated with the diagnostic workflow, providing lucrative growth opportunities to the market.
Future Market Scenario (2024 – 2031F)
According to nucleic acid isolation and purification market analysis, the market is expected to witness significant growth in the coming years due to the increasing popularity of nucleic acid-based diagnostics and the rapid expansion of the pipeline for RNA therapeutics. The increasing utilization of sequencing platforms for clinical diagnostics and rising research and development activities will further expand the market. The growing number of genetic and infectious diseases is expected to boost the demand for nucleic acid isolation and purification instruments and kits for diagnostic applications.
Report Scope
“Nucleic Acid Isolation and Purification Market Assessment, Opportunities and Forecast, 2017-2031F”, is a comprehensive report by Markets and data, providing in-depth analysis and qualitative and quantitative assessment of the current state of global nucleic acid isolation and purification market, industry dynamics, and challenges. The report includes market size, segmental shares, growth trends, opportunities, and forecast between 2024 and 2031F. Additionally, the report profiles the leading players in the industry mentioning their respective market share, business model, competitive intelligence, etc.
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